10 simptome ale mielomului multiplu

Myeloma de pierdere în greutate. Mielom multiplu: Simptome | Myelom-Gruppe Rhein-Main


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    METHODS The medical records, laboratory findings, and radiographic imaging studies of an year-old female patient with exacerbation of previously undiagnosed MM were reviewed. Radiographic studies depicted lumbar scoliosis and lateral spondylolisthesis.

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    Preoperative serum immunofixation electrophoresis showed a serum immunoglobulin A kappa paraprotein-peak; however, the patient had never been diagnosed with MM or reported any unexplained fever, night sweats, or weight loss indicative of MM. On postoperative day 1, the patient was evaluated by the hematology department for paraproteinemia.

    Serum electrophoresis showed decreased albumin, hypogammaglobulinemia, and suspicious broadening of the complement component in the beta region.

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    Postoperative imaging studies 19 weeks depicted progression of a previously visible intraosseous lesion, and anterior cortical breakthrough L5in addition to a soft tissue mass at the T10 level. Histological examination of iliac crest and T10 vertebral biopsies showed fatty marrow infiltration by plasma cells and plasma cell dyscrasia, proving the diagnosis of MM.

    The patient died 10 months after surgery due to complications related to a methicillin-resistant Staphylococcus aureus infection.

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